A deadly new program has one mission — wipe out every mutant on Earth. To achieve it, a secret organization has unleashed an army of unstoppable genetic cyborgs, combining mutant powers with deadly precision. Their first targets: the most dangerous and unpredictable mutants alive — Old Man Logan, Sabretooth, Domino, Lady Deathstrike, and Warpath.
But the hunters aren’t prepared for what happens when the Hulk gets caught in the crossfire. As old enemies and reluctant allies are forced to work together, the line between monster and hero blurs. With the fate of mutantkind at stake, the team must uncover who’s behind the creation of these hybrid killers before it’s too late. The war for survival begins — and it’s going to get savage.